Publications

August 2026: ZFP36L2 orchestrates stress-adaptive plasticity in regeneration and cancer.

Our Cancer Grand Challenges team REWIRE-CAN is finding ways to rewire colorectal cancer cells back into vulnerable states and holding them there. ZFP36L2 gives us a concrete handle on exactly that problem. It tells us which state a cell is in, what it takes to move it, and what goes wrong if you move it too slowly.

Karuna Ganesh

Jiang, Q., Raghavan, M.S., Rodriguez, A.M. et al. ZFP36L2 orchestrates stress-adaptive plasticity in regeneration and cancer. Nature (2026). https://doi.org/10.1038/s41586-026-10890-0

REWIRE-CAN
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